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School for Advanced Residue Analysis in Food
Presentation
Teaching Contributors
Programme
Registration
Location & Contact
Saraf Network
DG-Trade 2008 Session
Teaching modules
A
. Basis of the control
A1
Definitions
A2
Risk assessment, regulatory limits (as MRL) establishment
A3
Presentation of coumpounds to monitor
A31
Forbidden substances (96/23/EC - Group A)
A32
Veterinary drugs and contaminants (96/23/EC - Group B)
A4
International regulation
A41
Control regulation
A42
Official bodies for residues and contaminants in food
A43
Laboratory networks
A5
Consequences on the international market
B
. Basic principles of method used
B1
Screening methods
B11
ELISA
B12
RIA
B13
Receptor assay
B2
Sample preparation and purification
B21
Preparation
B211
Freeze drying
B212
Hydrolysis of conjugates
B22
Extraction
B221
LLE, ASE
B222
MSPD, SFE
B23
Purification
B231
SPE, HPLC
B232
IAC, Immunofiltration, MIR
B24
Laboratory Autmation
B3
Confirmatory techniques
B31
Mass spectrometry
B311
Sources (EI, PCI, NCI)
B312
Mass filters (Q, IT, BE, TOF, LRMS, HRMS, MS2, MSn)
B313
Acquisition modes (SIM, SCAN, MRM)
B32
Chromatography coupled to mass spectrometry
B321
GC
B322
LC (ESI, APCI, APPI)
B33
Hot topic in Mass Spectrometry
B331
Invited speakers on last development in mass spectrometry
B332
How mass spectrometry answers to emerging topics
C
. Quality in analytical laboratories
C1
European criteria : from 93/256/EC to 2002/657/EC
C2
Validation of analytical method
C3
Quality management (Assays, R&D)
List of teaching modules
T
Theory
P
Practical
Introduction
T
Welcome, introduction, programme
T
Conclusion of the session & debriefing
Regulation
T
Compounds to monitor
T
International Food Regulation (particular case of EU)
T
Risk assessment and regulatory limits
T
FVO requirements for third countries
Sample Preparation
T
Sample prep. Part I: introduction and decision tree
T
Sample prep. Part II: lyophilisation, hydrolysis...
T
Sample prep. Part III: extraction and purification
T
Particular case of application: Pesticides
T
Particular case of application: POPs
P
Particular case of application: Pesticides
P
Particular case of application: Antibiotics
P
Particular case of application: beta-Agonists
P
Particular case of application : Mycotoxins
Screening Methods
T
Advanced screening technologies: Antibody based assays
T
Advanced screening technologies: Cell based assays
P
Advanced screening technologies: Antibody based assays
P
Advanced screening technologies: Cell based assays
P
Bioassay applied to POPS
Confirmatory Methods
T
MS part I : Ionisation
P
Particular case of application: Boldenone
P
Particular case of application: Pesticides
P
Particular case of application: Persistant Organic Polutants
P
Particular case of application: Anabolic steroids
P
GC-MS data analysis
P
LC-MS data analysis
P
Isotopic dilution and quantification of dioxins
P
Statistical data analysis
T
MS part II : Detection and acquisition
T
Chromatographic-MS coupling
T
GC-HRMS for the measurment of POPS
P
Structural elucidation (beta-agonists compounds)
P
GC-MS practical aspects (optimisation, maintenance)
P
LC-MS practical aspects (optimisation, maintenance)
P
Particular case of application: Corticosteroids
P
Particular case of application: Perfluorinated compounds
Quality in analytical laboratories
T
European Criteria
T
Validation of analytical methods
T
Quality management
P
European Criteria
P
Validation of analytical methods
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